Synthesis of n-disubstituted amides by reaction of amides with c

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564160, 564215, 564224, C07C23305

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active

050416596

ABSTRACT:
Disclosed is a method which comprises introducing into a reaction zone a feed which comprises a hydroxyl compound reactant, R"OH, at least one amide reactant selected from R-CONH.sub.2 and R-CONHR', and an inorganic catalyst, thereby reacting R"OH with said amide reactant to produce a rection mixture containing at least one disubstituted amide selected from R-CONHR".sub.2 and R-CONHR'R", wherein

REFERENCES:
patent: 4853485 (1989-08-01), Bellis
Geivandor, Zh Org Khim 1983, 19, 738-739.
Kashiwagi et al, Nippon Kagako Kaishi, 1980, pp. 279-281.
Cheesman et al., J Chem Soc, 1962, 5277-5280.
Watanabe et al, Bull. Chem. Soc. Japan, 1983, 56, 2647-2651.

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