Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-12-03
1976-09-07
Thomas, Jr., James O.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424244, 424267, 424274, 424275, 260239BF, 26032635, 2603322A, C07D40500
Patent
active
039793966
ABSTRACT:
Synthesis of biotin from 4-carbomethoxy-2-(4,5-dihydrothiophen-3(2H)-one)-valeric acid methyl ester, and dihydrothiophene intermediates in this synthesis.
REFERENCES:
Harris et al., "J.A.C.S.", (1944), vol. 66, pp. 1756, 1757.
Groggins, "Processes In Organic Synthesis", fourth ed., (1952), p. 489.
Confalone Pasquale Nicholas
Pizzolato Giacomo
Uskokovic Milan Radoje
Gaither Richard A.
Hoffmann-La Roche Inc.
Leon Bernard S.
Siegel A.
Thomas, Jr. James O.
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