Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2005-09-21
2010-02-09
Jiang, Shaojia Anna (Department: 1623)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S400000, C424S489000, C514S053000
Reexamination Certificate
active
07658949
ABSTRACT:
The invention relates to a process for the surface-energy passivation of lactose which is intended for use as an excipient in the production of inhalable powders, and the use of such optimised carrier materials in the manufacture of inhalable powders.
REFERENCES:
patent: 3634582 (1972-01-01), Hartley et al.
patent: 5478578 (1995-12-01), Arnold et al.
patent: 7132115 (2006-11-01), Musa et al.
patent: 2004/0062719 (2004-04-01), Buckton et al.
patent: 2006/0025326 (2006-02-01), Lankinen et al.
patent: WO 92/18110 (1992-10-01), None
patent: WO 95/05805 (1995-03-01), None
patent: WO 00/30265 (2000-05-01), None
patent: WO 01 76560 (2001-10-01), None
patent: WO 02 07705 (2002-01-01), None
patent: WO 02/30389 (2002-04-01), None
patent: WO 02/30390 (2002-04-01), None
patent: WO 02/30928 (2002-04-01), None
patent: WO 02/45682 (2002-06-01), None
patent: WO 03/000265 (2003-01-01), None
patent: WO 03/017970 (2003-03-01), None
patent: WO 03/017979 (2003-03-01), None
Hogan, SE, Buckton, G (2001) The Application of Near Infrared Spectroscopy and Dynamic Vapor Sorption to Quantify Low Amorphous Contents of Crystalline Lactose, Pharmaceutical Research, vol. 18, No. 1, p. 112-116.
Sebhatu, T., Angberg, M., Ahlneck, C. (1994) Assessment of the degree of disorder in crystalline solids by isothermal microcalorimetry. International Journal of Pharmaceutics, vol. 104, p. 135-144.
Briggner, L.-E., Buckton, G., Bystrom, K., Darcy, P. (1994) The use of isothermal microcalorimetry in the study of changes in crystallinity induced during the processing of powders. International Journal of Pharmaceutics, vol. 105, p. 125-135.
Buckton, Graham et al, “The Use of Gravimetric Studies to Assess the Degree of Crystallinity of Predominantly Crystalline Powders”,International Journal of Pharmaceutics, Amsterdam: Bd. 123, Nr. 2, 1995, pp. 265-271.
Naini, Venkatesh et al, “Physicochemical Stability of Crystalline Sugars and Their Spray-Dried Forms: Dependence Upon Relative Humidity and Suitability for Use in Powder Inhalers”,Drug Development and Industrial Pharmacy, New York, New York: US, Bd. 24, Nr. 10, 1998, pp. 895-909.
Dilworth, Sarah E. et al, “Approaches to Determine the Enthalpy of Crystallisation, and Amorphous Content, of Lactose From Isothermal Calorimetric Data”,International Journal of Pharmaceutics, Amsterdam NL: Bd. 284, Nr. 1-2, Sep. 11, 2004, pp. 83-94.
Berlin, E., et al. “Calorimetric Measurement of the Heat of Desorption of Water Vapor from Amorphous and Crystalline Lactose”,Thermochimica Acta, Bd. 2, 1971, Elsevier Publishing Co., Amsterdam, pp. 150-152.
Steckel, Hartwig et al. “Calorimetric Study on Amorphous Lactose During and After Re-Crystallization at Different Relative Humidity”,Pharmazeutische Industrie, 2005 Germany: Bd 67, Nr. 6 pp. 709-712.
Newell, Helen E. et al., The Use of Inverse Phase Gas Chromatography to Measure the Surface Energy of Crystalline, Amorphous, and Recently Milled Lactose, Pharmaceutical Research, vol. 18, No. 5, 2001, pp. 662-666, Plenum Publishing Corp., New York, USA.
Zeng, Xian Ming et al., The Influence of Lactose Carrier on the Content Homogeneity and Dispersability of Beclomethasone Dipropionate from Dry Powder Aerosols, International Journal of Pharmaceutics, vol. 197, 2000, pp. 41-52, Elsevier Science B.V., The Netherlands.
Mueller Bernd Wilhelm
Steckel Hartwig Andreas
Timmermann Inga-Lis
Trunk Michael
Boehringer Ingelheim International GmbH
Devlin Mary-Ellen M.
Goon Scarlett
Jiang Shaojia Anna
Morris Michael P.
LandOfFree
Surface modification of lactose excipient for use in powders... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Surface modification of lactose excipient for use in powders..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Surface modification of lactose excipient for use in powders... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4205647