Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...
Patent
1990-02-14
1992-01-28
Naff, David M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Stablizing an enzyme by forming a mixture, an adduct or a...
435189, 4353201, 435256, 435 10, 435 14, 435 47, 424 944, 536 27, C12N 996, C12N 902, A61K 3750
Patent
active
050843907
ABSTRACT:
Recombinant Cu/Zn superoxide dismutase (SOD) polymers having an extended in vivo half-life composed of SOD monomers covalently coupled to each other, carboxy terminus to amino terminus, by a polypeptide spacer such as a fragment of the hinge region of an immunoglobulin.
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Hallewell Robert A.
Mullenbach Guy
Chiron Corporation
Naff David M.
Patterson Jr. Charles L.
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