Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-04-22
1995-07-18
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514349, 546297, 546307, A61K 3144, C07D21302
Patent
active
054341728
ABSTRACT:
Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower alkyl group, A and B may be the same or different from each other and each represent .dbd.N-- or .dbd.CH--, E represents an aromatic 6-membered cyclic group, which may have 1 or 2 nitrogen atoms in the ring, and be substituted with 1 to 3 substituents which may be the same or different from one another with the proviso that a combination of R.sup.1 which is a hydrogen atom, lower alkyl group, nitro group or amino group which may be protected, R.sup.2 and R.sup.3 which are each a hydrogen atom, A and B which are each .dbd.CH-- and E which is a phenyl group which may be substituted with 1 to 3 substituents G which may be the same or different from one another is excluded,
or pharmacologically acceptance salts of them, have an excellent antitumo-activity.
REFERENCES:
Chemical Abstracts, vol. 96, No. 21. Abstract 190.694q p. 672 May 24, 1982.
Beilsteins Handbuch Der Organischen Chemie, 4th Edition, 3rd Supplement, vol. 14, Part 3, 1974, pp. 2092-2093.
J. Med. Pharm. Chem., vol. 1, No. 3, 1959, pp. 197-210, M. C. Kloetzel, et al.
Asada Makoto
Iijima Atsumi
Kitoh Kyosuke
Kotake Yoshihiko
Koyanagi Nozomu
Davis Zinna N.
Eisai Co. Ltd.
Ivy C. Warren
LandOfFree
Sulfonamide derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sulfonamide derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfonamide derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2419123