Substituted tetralins, chromans and related compounds in the tre

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514369, 514373, 514372, 514365, 548207, 548214, 548159, 548203, C07D27502, C07D27504, A01N 4380, A01N 4378

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active

059984511

ABSTRACT:
Substituted tetralins, chromans and related compounds which, by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction and related disease states in mammals, pharmaceutical compositions thereof, a method of treatment therewith, and to intermediates useful in the synthesis thereof.

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