Substituted pyridylamino indoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514318, 514212, 5142352, 514255, 5462774, 5462781, 5462721, 546256, 546143, 546193, 546194, 544131, 544124, 544360, 540597, A61K 3144, C07D40112

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active

060228806

ABSTRACT:
There are disclosed various compounds of the formula below, ##STR1## where R, R.sub.1, W, X, Y and Z are as defined in the specification; which are useful for alleviating various memory dysfunctions such as Alzheimer's disease, as modulators of neurotransmitter functions such as serotonergic and adrenergic, and as such are useful as antidepressants, anxiolytics, atypical antipsychotics, antienmtics, and for the treatment of personality disorders such as obsessive compulsive disorder.

REFERENCES:
patent: 5102891 (1992-04-01), Effland et al.
Shutske. Medicinal Chemistry Approaches to AD and Other Dementias Symposium. Div. of Educational Services, Mayor Clinic. Jacksonville. Florida. Sep. 13, 1993.

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