Substituted pyridines and 2-oxo-1,2-dihydropyridines

Details Substituted pyridines and 2-oxo-1,2-dihydropyridines Substituted pyridines and 2-oxo-1,2-dihydropyridines

1994-04-29

1996-02-20

Fan, Jane

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546276, C07D40110, A61K 3144

Patent

active

054929237

ABSTRACT:
Substituted pyridines and 2-oxo-1,2-dihydropyridines are prepared by reaction of correspondingly substituted halogenobenzenes with tetrazolylboronic acids. The substituted pyridines and 2-oxo-1,2-dihydropyridines according to the invention can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.

REFERENCES:
Chemical Abstract vol. 114 (1991) 247 301 x.
Chemical Abstract vol. 115 (1991) 114531x.
Chemical Abstract vol. 115 (1991) 159 173 v.
Russell Ross, The Journal of Cell Biology, vol. 50, 1971, pp. 172-186.
Wade Organic Chemistry p. 349. Prentice-Hall Inc. 1987.
Clark et al. Principles of Psychopharmacology. Academic Press. New York. 1970. p. 167.

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