Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-03-06
1999-08-03
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540575, A61K 3155, C07D40314
Patent
active
059325712
ABSTRACT:
The present invention relates to novel enzamide derivatives of the formula: ##STR1## stereoisomers thereof, and pharmaceutically acceptable salts thereof which are useful as histamine receptor antagonists and tachykinin receptor antagonists. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis.
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Bratton Larry D.
Dalton Christopher R.
Kane John M.
Kudlacz Elizabeth M.
Maynard George D.
Coleman Brenda
Hoechst Marion Roussel Inc.
Kurys Barbara E.
Shah Mukund J.
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