Substituted mono- and bipyridylmethylpyridones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514335, 546256, 546261, C07D40114, C07D40110, A61K 3144, A61K 3153

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active

054079489

ABSTRACT:
Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halogenopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.

REFERENCES:
patent: 5128327 (1992-07-01), Chakravarty et al.
patent: 5149699 (1992-09-01), Ellingboe et al.
The Journal of Cell Biology, vol. 50, 1971, pp. 172-186; "The Smooth Muscle Cell", R. Ross.

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