Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-05-19
1985-10-01
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514307, 544363, 544384, 544395, 546147, 546149, A61K 3147, A61K 31495, C07D40106
Patent
active
045446571
ABSTRACT:
Substituted isoquinolines of the formula ##STR1## wherein R is lower alkoxy, n is the integer zero or 1, and A is ##STR2## wherein R.sub.1 is phenyl, halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and pharmaceutically acceptable acid addition salts thereof, are described. The compounds of formula I are useful in the treatment of cerebral and cardiac ischemias.
REFERENCES:
patent: 3795675 (1974-03-01), Laguzzi
patent: 4260611 (1981-04-01), Bartmann et al.
Israilov, et al., "Chemical Abstracts", vol. 100, 1984, Col. 100: 206493e.
Bruderer Hans
Kierstead Richard W.
Mullin, Jr. John G.
Nakamura Keiji
O'Brien Jay P.
Hoffmann-La Roche Inc.
Hollrah Glennon H.
Isgro William G.
Leon Bernard S.
Saxe Jon S.
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