Substituted diphenyl indanone, indane and indole compounds and a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514475, 514544, 514546, 514617, 514640, 514717, 549430, 549453, 549550, 558388, 560 56, 560 57, 560221, 564180, 564265, 568659, 568808, 568809, A61K 31335, C07C25500, C07C 6976, C07C 6952

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active

061274070

ABSTRACT:
The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.

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