Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Reexamination Certificate
2011-07-26
2011-07-26
Puttlitz, Karl J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
C562S480000
Reexamination Certificate
active
07985876
ABSTRACT:
The invention relates to novel substituted dibenzoic acid derivatives of formula (I), wherein A represents a group of formula (II) or (III), to methods for producing the same, and to their use in the treatment and/or prophylaxis of diseases. The invention also relates to the use of said substances in the production of drugs for the treatment and/or prophylaxis of diseases, especially in the treatment and/or prevention of cardiovascular diseases.
REFERENCES:
patent: 6180656 (2001-01-01), Furstner et al.
patent: 6387940 (2002-05-01), Straub et al.
patent: 6410740 (2002-06-01), Straub et al.
patent: 6414009 (2002-07-01), Straub et al.
patent: 6451805 (2002-09-01), Straub et al.
patent: 6462068 (2002-10-01), Straub et al.
patent: 6864287 (2005-03-01), Alonso-Alija et al.
patent: 7087644 (2006-08-01), Alonso-Alija et al.
patent: 2004/0082798 (2004-04-01), Alonso-Alija et al.
patent: 2004/0176446 (2004-09-01), Alonso-Alija et al.
patent: 2007/0179139 (2007-08-01), Alonso-Alija et al.
patent: 2008/0058314 (2008-03-01), Alonso-Alija et al.
patent: 200074150 (2001-04-01), None
patent: 0341551 (1989-11-01), None
patent: WO-98/16223 (1998-04-01), None
patent: WO-98/16507 (1998-04-01), None
patent: WO-98/23619 (1998-06-01), None
patent: 0119355 (2001-02-01), None
patent: WO-01/19355 (2001-03-01), None
patent: WO-01/19776 (2001-03-01), None
patent: WO-01/19778 (2001-03-01), None
patent: WO-01/19780 (2001-03-01), None
patent: WO-02/070462 (2002-09-01), None
patent: WO-02/070510 (2002-09-01), None
Ullmann's Encyclopedia of Industrial Chemistry, Copyright © 2002 by Wiley-VCH Verlag GmbH & Co. KGaA , pp. 1-51.
Fn Ko et al.: “YC-1, A Novel Activator of Platelet Guanylate Cyclase,” Blood, 84, 1994, pp. 4226-4233.
A. Mulsch et al.: “Effect of YC-1, an NO-independent, Superoxide-Sensitive Stimulator of Soluble Guanylyl Cyclase, on Smooth Muscle Responsiveness to Nitrovasodilators,” British Journal of Pharmacology, 120, 1997, pp. 681-689.
D. B. Glass et al.: “Stimulation of Human Platelet Guanylate Cyclase by Fatty Acids,” The Journal of Biological Chemistry, vol. 252, No. 4, Feb. 25, 1977, pp. 1279-1285.
D. J. Pettibone et al.: “A Structurally Novel Stimulator of Guanylate Cyclase with Long-Lasting Hypotensive Activity in the Dog,” European Journal of Pharmacology, 116, 1985, pp. 307-312.
S-M Yu et al.: “Vasorelaxant Effect of Isoliquiritigenin, a Novel Soluble Guanylate Cyclase Activator, in Rat Aorta,” British Journal of Pharmacology, 114, 1995, pp. 1587-1594.
R. Gerzer et al.: “Soluble Guanylate Cyclase Purified from Bovine Lung Contains Heme and Copper,” FEBS Letters, vol. 132, No. 1, Sep. 1981, pp. 71-74.
M. Hoenicka et al.: “Purified Soluble Guanylyl Cyclase Expressed in a Baculovirus/Sf9 System: Stimulation by YC-1, Nitric Oxide, and Carbon Monoxide,” J. Mol. Med, 77, 1999, pp. 14-23.
L. J. Ignarro: “Regulation of Cytosolic Guanylyl Cyclase by Porphyrins and Metalloporphyrins,” Advances in Pharmacology, vol. 26, 1994, pp. 35-65.
A. Mulsch et al.: “Potentiation of Vascular Responses to Non-Donors by An No-Independent Activator of Soluble Guanylyl Cyclase,” Naunyn Schmiedebergs Arch. Pharmacol. 355, R47.
O. V. Evgenov et al.: “NO-Independent Stimulators and Activators of Soluble Guanylate Cyclase: Discovery and Therapeutic Potential,” Nature Reviews Drug Discovery, vol. 5, Sep. 2006, pp. 755-768.
J-P Stasch et al.: “Targeting the Hem-Oxidized Nitric Oxide Receptor for Selective Vasodilatation of Diseased Blood Vessels,” The Journal of Clinical Investigation, vol. 116, No. 9, Sep. 2006, pp. 2552-2561.
Becker Eva-Maria
Hahn Michael
Knorr Andreas
Lang Dieter
Schlemmer Karl-Heinz
Bayer Schering Pharma Aktiengesellschaft
Blankinship Thomas
King Karen B.
Puttlitz Karl J
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