Substituted cyclic carbonyls and derivatives thereof useful as r

Details Substituted cyclic carbonyls and derivatives thereof useful as r Substituted cyclic carbonyls and derivatives thereof useful as r

1996-11-22

1998-09-22

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514 79, A61K 3155

Patent

active

058114220

ABSTRACT:
This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection. A representative compound of the invention is the compound of formula: ##STR1## wherein R.sup.22 and R.sup.23 are allyl.

REFERENCES:
patent: 4749681 (1988-06-01), Evers et al.
patent: 5610294 (1997-03-01), Lam et al.
J. Org. Chem., 44, 1391-1397, 1997.
Tetrahedron Lett., 28, 3103-3106, 1987.
Tetrahedron Lett., 28, 5129-5132, 1987.
Kempf et al., J. Org. Chem., 57, 5692-5700, 1992.

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