Substituted, bicyclic 8-pyrrolidinoxanthines, and methods...

Details Substituted, bicyclic 8-pyrrolidinoxanthines, and methods... Substituted, bicyclic 8-pyrrolidinoxanthines, and methods...

2011-02-15

2011-02-15

Berch, Mark L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S263200, C514S263220, C540S580000, C544S268000, C546S113000, C548S453000

Reexamination Certificate

active

07888343

ABSTRACT:
The present invention involves substituted bicyclic 8-pyrrolidinoxanthines and their derivatives of formula I:wherein the various R groups are defined herein. The present invention also comprises pharmaceutical compositions comprising them as well as processes for the preparation of these compounds and methods for the treatment of metabolic disorders such as type-2 diabetes, insulin resistance, hyperglycemia, arteriosclerosis diseases and the like through the administration of said compositions.

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