Substituted azacyclohexyl derivatives

Details Substituted azacyclohexyl derivatives Substituted azacyclohexyl derivatives

1991-10-18

1992-09-15

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Plant extract or plant material of undetermined constitution

514255, 340468, 544368, C07D52100, A61K 31395

Patent

active

051478706

ABSTRACT:
The invention relates to the preparation of substituted azacyclohexyl derivatives of rifamycins of the formula ##STR1## and salts thereof in which R.sub.1 is hydrogen or trialkylacetyl, R.sub.2 is hydrogen or acetyl and R.sub.3 is alkyl, which exhibit valuable pharmacological properties.

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patent: 4876258 (1989-10-01), Kump et al.
patent: 4916126 (1990-04-01), Traxler et al.
patent: 4918066 (1990-04-01), Kump
patent: 5003070 (1991-03-01), Kump et al.
patent: 5053510 (1991-10-01), Kump
Burger's Med. Chem. 4th Ed. part III pp. 320, 321 & 577, John Wiley & Sons, New York 1979.
Taguchi et al., Chem. Pharma. Bull. vol. 33, No. 5 pp. 2133-2136 (1965).

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