Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1986-05-27
1987-11-10
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
514569, 562466, 560101, 560 57, 560 56, C07C 6333
Patent
active
047058919
ABSTRACT:
Substituted .alpha.-[2'-tricyclo[3.3.1.1.sup.3,7 ]decylidene]-benzeneacetic acid derivatives of the formula: ##STR1## where the R.sup.1, R.sup.2 and R.sup.3 substituents are independently selected from hydrogen, lower alkyl, lower alkoxy, halogen and trifluoromethane, provided that at least one of such substituents is hydrogen have antihypoxia, anticonvulsant and/or antiparkinson activities.
REFERENCES:
patent: 3624126 (1971-11-01), Narayanan
Aigami et al., "Biologically Active Polycycloalkanes.1 Antivirial Adamantane Derivatives," J. Med. Chem. 18, 713-721 (1975).
CA 83:96537t, Inst. Org. Khim., Danilenko et al., "Bacteriostatic Effect of Adamantanecarboxylic Acids".
Georgiev Vassil S.
Mullen George B.
Bunnell David M.
Killos Paul J.
Pennwalt Corporation
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