Submucosa as a growth substrate for islet cells

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of culturing cells in suspension

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C12N 500

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056959982

ABSTRACT:
A cell culture growth substrate comprising submucosal tissue of a warm-blooded vertebrate and a method for culturing eukaryotic cells are described. Submucosal tissue used in accordance with the present invention supports the proliferation and differentiation of eukaryotic cells when said cells are contacted with submucosal tissue under conditions conducive to cell proliferation.

REFERENCES:
patent: 4439521 (1984-03-01), Archer et al.
patent: 4743552 (1988-05-01), Friedman et al.
patent: 4829000 (1989-05-01), Kleinman et al.
patent: 4902508 (1990-02-01), Badylak et al.
patent: 4956178 (1990-09-01), Badylak et al.
patent: 5266480 (1993-11-01), Naughton et al.
patent: 5275826 (1994-01-01), Badylak et al.
patent: 5281422 (1994-01-01), Badylak et al.
patent: 5352463 (1994-10-01), Badylak et al.
patent: 5372821 (1994-12-01), Badylak et al.
patent: 5478739 (1995-12-01), Slivka et al.
patent: 5518915 (1996-05-01), Naughton et al.
Long-Term Production of Insulin by Isolated Rabbit Pancreatic Islets in Suspension Culture. Boder, G.B., Root, Mary A., Chance, R.E., and Johnson, I.S. J. Cell Biol. 39: 16a, 1968 abs. #34.
Extended Production of Insulin by Isolated Rabbit Pancreatic Islets; Evidence for Biosynthesis of Insulin. Boder, G.B., Root, Mary., Chance, R.E. Johnson, I.S. Proc. Soc. Exptl. Biol. Med. 131:507-513, 1969.
Visible Light Inhibits Growth of Chinese Hamster Ovary Cells. George B. Boder, Richard J. Harley, Walter Kleinschmidt, and Daniel C. Williams. European J. Cell Biol. #1 31:132-136, Jul. 1983.
Long Term Monolayer Cultures of Islet Cells from Neonatal Mice. Boder, G.B., Shaw, W.N. and Smith, R.E. J. Cell Biol. 59: 29a, Nov. 1973 abs.
Changes in the Islets of Langerhans in the Obese Zucker Rat. Lars-Inge Larsson, George B. Boder, and Walter N. Shaw. Lab. Invest. #6 36:593-598, 1977.
Mineralization in Cultured Adult Rat Bone Cells. Evaluation by Video Time Lapse, Scanning Electron Microscopy and Energy Dispersive X-ray Analyses. D.C. Williams, D.C. Paul, C.C. Johnston, Jr., and G.B. Boder. J. Cell Biol. 91: 22a, 1981 abs. #1031.
Introduction to techniques in Mammalian Cell Culture. George B. Boder and Robert N. Hyll. Manual of Industrial Microbiology and Technology, Ed. A.L. Demain and N.A. Solomon, pp. 248-261, 1986.
Large Scale Production of Monoclonal Antibodies in Suspension Culture. M.P. Backer, L.S. Metzger, P.L. Slaber, K.L. Nevitt, and G.B. Boder. Biotechnology and Bioengineering 32: 993-1000, 1988.
17-.beta. Estrodiol Inhibits IL-6 Production by Bone Marrow Stromal Cells and Osteoblasts In Vitro: A Potential Mechanism for the Antiosteoporotic Effects of Estrogens. Girasole et al., The Journal of Clinical Investigation 89:883-891, Mar. 1992.
Mammalian Cell Cultures for Genetically Engineered Products. Boder, G.B. Toxicologic Pathway, vol. 17, No. 4, p. 827, 1989.
Directed Connective Tissue Remodeling Upon a Biologic Collagen Substrate. S.T. Badylak, G.B. Boder, R. Morff, G. Lantz J. Cell Biochem. Supplement 16F, p. 124, 1992 abs. #CE027.
Mini-Review: Islet Transplantation to Create a Bioartificial Pancreas. Antonios G. Mikos, Maria G. Papadaki, Stylianos Kouvroukoglou, Susan L. Ishang, and Robert C. Thomson, Biotech. and Bioengineering, vol. 43, pp. 673-677 (1994).
Tissue Engineering of Islet Gland Equivalent. CY Kuo, GA Burghen, HG Herrod and TW Budd. Biological Abstracts A302 (1742), 1994 Abs. #1742.
Biohybrid Islet-Gland Equivalent for Transplantation. Chao-Ying, George A. Burghen, and Henry G. Herrod. Journal of Cellular Biochemistry, Supplement 18C, PZ110, Feb. 13-26, 1994 Abs. #PZ110.
Basement Membrane Complexes with Biological Activity. Hynda K. Kleinman, Mary L. McGarvey, John R. Hassell, Vicki L. Star, Frances B. Cannon, Gordon W. Laurie, and George R. Martin. Biochemistry 25:312-318, 1986.
Formation of Pseudoislets from Human Pancreatic Cultures. Chao Y. Kuo, Henry G. Herrod, and George A. Burghen. Pancreas vol. 7, No. 3, pp. 320-325, 1992.
Cultures of Animal Cells: A Manual of Basic Technique. R. Ian Freshney. Chapters 12 and 13, pp. 119-143. Alan R. Liss, Inc., New York, 1994.
Housseiny, El et al., Orthotopic Implantation of Primary Bladder Submucosa: An Animal Model for Bladder Cancer Study, Cancer Research, vol. 43:617-620, Feb. 1983.
Kashtan, H. et al., Intra-rectal injection of tumor cells: a novel animal model of rectal cancer, Surgical Oncology, 1:251-256, Jun. 1992.
Sigma 1994 Catalogue and Price List, Plant Cell Culture Equipment, p. 160.
Bioartificial Organs. Richard Skalak and Fred Fox, eds. Tissue Engineering, Chapter V, pp. 209-242, 1988.

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