Chemistry: natural resins or derivatives; peptides or proteins; – Natural resins or derivatives – Tall oil or derivative used as starting material in process,...
Reexamination Certificate
2008-06-17
2008-06-17
Borin, Michael (Department: 1631)
Chemistry: natural resins or derivatives; peptides or proteins;
Natural resins or derivatives
Tall oil or derivative used as starting material in process,...
C560S116000, C560S117000
Reexamination Certificate
active
07388070
ABSTRACT:
A method for the structure-based identification and selection of inhibitors of processivity factor binding to protein is disclosed herein. Characterization of the protein/processivity factor interface is given. Methods for the structure-based inhibition of processivity factor binding to protein are also given. One embodiment includes a class of peptidomimetics that mimic helical portions of proteins. In addition, methods of treatment of various diseases are given, using the inhibitors of the invention.
REFERENCES:
Lukas et al. J. Med. Chem., 42 (5), 910-919, Feb. 1999.
Bridges Kristie Grove
Coen Donald
Elkin Carl
Hogle James
Lokey Scott
Borin Michael
Foley & Lardner LLP
President and Fellows of Harvard College
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