Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-06-02
1998-04-28
Kunz, Gary L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 271, 536 281, C07H 100, C07H 19073, C07H 19173
Patent
active
057445974
ABSTRACT:
A stereoselective anion glycosylation process for preparing beta- and alpha-anomer enriched 2', 2'-difluoro-2'-deoxynucleosides and 2'-deoxy-2'-fluoronucleosides by reacting an alpha- or beta-anomer enriched 2-deoxy-2-fluorocarbohydrate or 2-deoxy-2,2-difluorocarbohydrate with at least a molar equivalent of a salt of a nucleobase derivative in an inert solvent.
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Chou Ta-Sen
Grossman Cora S.
Hertel Larry Wayne
Holmes Richard E.
Jones Charles D.
Barrett Brian P.
Boone David E.
Eli Lilly and Company
Kunz Gary L.
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