Stable solutions and processes for their preparation

Details Stable solutions and processes for their preparation Stable solutions and processes for their preparation

1977-09-15

1979-02-06

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424261, 424250, 424 14, 215DIG3, 215365, C07D51902

Patent

active

041385659

ABSTRACT:
Solutions of certain hydrogenated ergopeptide alkaloids in mixtures of pharmacologically acceptable alcohols and water have improved stability. Preferred solvents are mixtures of ethanol, propylene glycol and glycerol containing from 15-40% wt. of water and having dielectric constants between 34 and 46. With these solutions it is not essential to carry out the filing operation under an inert atmosphere.

REFERENCES:
patent: 2073954 (1937-03-01), Wolf
patent: 2507831 (1950-05-01), Stoll et al.
patent: 3113133 (1963-12-01), Hofmann et al.
patent: 3652569 (1972-03-01), Stadler et al.
patent: 3666762 (1972-05-01), Guttmann et al.
patent: 3755328 (1973-08-01), Stadler et al.
patent: 3901891 (1975-08-01), Fehr et al.

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