Stable cell lines expressing the CFTR protein or a mutant of thi

Details Stable cell lines expressing the CFTR protein or a mutant of thi Stable cell lines expressing the CFTR protein or a mutant of thi

1997-06-12

1999-03-30

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

4353201, 435325, 435 691, 536 231, 536 241, C12Q 100, C12P 2106, C12N 1500, C07H 1700

Patent

active

058887229

ABSTRACT:
The invention relates to a recombinant nucleic acid, characterized in that it comprises:

REFERENCES:
Costa de Beauregard, "Establishment of Kidney Epithelial Cell Lines Expressing Wild Type and CFTR (.DELTA.F508) With an Epitope Tag in View of Functional Studies on CFTr (.DELTA.F508) Trafficking", ICF(M)A (1996).
Bergeron et al, "Calnexin: a membrane-bound chaperone of the endoplasmic reticulum", TIBS 19(3):124-128 (1994).
Yang et al, "The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment", Proc. Natl. Acad. Sci. USA 90:9480-9484 (1993).
Pind et al, "Participation of the Endoplasmic Reticulum Chaperone Calnexin (p88, IP90) in the Biogenesis of the Cystic Fibrosis Transmembrane Conductance Regulator", Journal of Biological Chemistry 269(17):12784-12788 (1984).
Robine et al, "Regulatory Sequences on the Human Villin Gene Trigger the Expression of a Reporter Gene in a Differentiating HT29 Intestinal Cell Line", Journal of Biological Chemistry 268(15):11426-11434 (1993).
Hammond et al, "Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control", Proc. Natl. Acad. Sci. USA 91:913-917 (1994).
Hammond et al, "Folding of VSV G Protein: Sequential Interaction with BiP and Calnexin", Science 266:456-458 (1994).
Jackson et al, "Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p. 88, IP90)", Science 263-384-390 (1994).
Rajagopalan et al, "Retention of Unassembled Components of Integral Membrane Proteins by Calnexin", Science 263:387-390 (1994).
Kreis, "Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface", The EMBO Journal 5(5):931-941 (1986).

Affiliated with

Also associated with

Rating

Stable cell lines expressing the CFTR protein or a mutant of thi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stable cell lines expressing the CFTR protein or a mutant of thi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable cell lines expressing the CFTR protein or a mutant of thi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1213390