Stabilized interferon alpha solutions

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

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Details

424 851, 53038823, A61K 3766, A61K 3821, A61K 3819, C07K 1452

Patent

active

057629234

ABSTRACT:
An aqueous interferon composition which comprises an amount of interferon-alpha dissolved in water with a non-ionic detergent and benzyl alcohol in amounts sufficient to stabilize the amount of interferon-alpha, which composition contains an amount of acidic buffer which provides a pH of 4.5 to 6.0, and may also contain an isotonizing agent.

REFERENCES:
patent: 5503827 (1996-04-01), Woog et al.
Patent Abstracts of Japan, vol. 11, No. 139, JP61277633, Toray Ind. Inc. (Dec. 8, 1986).
English Abstract for Document B1 (61/277633).
Abstract corresponding to EP 0 440 100.

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