Stabilized antibiotic SF-837 preparation

Details Stabilized antibiotic SF-837 preparation Stabilized antibiotic SF-837 preparation

1974-08-09

1976-06-08

Rosen, Sam

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 35, 424115, A61K 936, A61K 31765, A61K 3500

Patent

active

039624196

ABSTRACT:
This invention relates to an antibiotic preparation comprising a macrolide antibiotic, which is highly stabilized against an acidic solution or acidic substance because of the presence of a polymer component incorporated with the macrolide antibiotic by specific solvent treatment, and to a process for the production of such antibiotic preparation. The antibiotic preparation of this invention overcomes the defect of macrolide antibiotics that they are easily decomposed upon contact with an acidic solution or acidic substance.

REFERENCES:
patent: 3576760 (1971-04-01), Gould et al.
patent: 3608063 (1971-09-01), Banker
patent: 3629392 (1971-12-01), Banker
patent: 3691090 (1972-09-01), Kitajima
patent: 3829564 (1974-08-01), Merry et al.

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