Stabilization of 16-oxygenated prostanoic acid derivatives

Details Stabilization of 16-oxygenated prostanoic acid derivatives Stabilization of 16-oxygenated prostanoic acid derivatives

1980-07-29

1981-11-17

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424305, 424317, 424362, A61K 3174, A61K 31215, A61K 3119

Patent

active

043011462

ABSTRACT:
A stable solid dosage form of the compound .+-.methyl(7-[3(.alpha.)-hydroxy-2-.beta.-(4(RS)-4-hydroxy-4-methyl-trans- 1-octen-1-yl)-oxycyclopent-1.alpha.-yl]heptanoate, said solid dosage form comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrolidone per part of said compound.

REFERENCES:
patent: 3826823 (1974-07-01), O'Rourke et al.
patent: 3965143 (1976-06-01), Collins et al.
patent: 4058623 (1977-11-01), Hoffmann et al.
patent: 4127647 (1978-11-01), Sato et al.

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