Spray dried lactose and process for preparing the same

Details Spray dried lactose and process for preparing the same Spray dried lactose and process for preparing the same

1987-03-18

1989-02-07

Shine, W. J.

Sugar, starch, and carbohydrates

Products

Sugars only

127 15, C13K 500

Patent

active

048029262

ABSTRACT:
The invention relates to a spray dried lactose suitable for use as component of tablets and to a process for preparing same. The lactose is predominantly crystalline and contains at most 50% by weight of amorphous lactose. At least 50% by weight of the crystalline lactose consists of particles below 50 .mu.m. The preparation process comprises a step of suspending crystalline alpha-lactose hydrate at 0.degree.-90.degree. C. in a saturated lactose solution, and a spray drying step. The temperature of the suspension is kept substantially constant until the time of spray drying in order to minimize crystallization and dissolution events.

REFERENCES:
patent: 2088606 (1937-08-01), Peebles et al.
patent: 3639170 (1972-02-01), Hutton et al.
patent: 3802914 (1974-04-01), Nczbed

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