Spironolactone process

Details Spironolactone process Spironolactone process

1979-04-13

1980-07-08

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955C, 2603971, 2603974, C07J 2100

Patent

active

042117011

ABSTRACT:
Spironolactone (VIII) is produced from ethisterone (I) by formation of the lactone (IV), a halo lactone (VI) and a .DELTA.4,6-lactone (VII).

REFERENCES:
patent: 3194803 (1965-07-01), Colton
patent: 3452008 (1969-06-01), Buzby, Jr. et al.
patent: 3773758 (1973-11-01), Weier

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