Spheronization process using charged resins

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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Details

424 781, 424502, 424 7816, A61K 914, A61K 918

Patent

active

053505840

ABSTRACT:
The invention comprises a novel process for the spheronization of charged resins. Spherical multiparticlates are produced which range in size from 0.3 mm to 3 mm in diameter. The spherical particle product is microcrystalline-free. The process consists of the steps of mixing followed by wet granulation, spheronization and drying.

REFERENCES:
patent: 4808413 (1989-02-01), Joshi et al.
patent: 4851421 (1989-07-01), Iwasaki et al.
patent: 4938967 (1990-07-01), Newton et al.
patent: 4976949 (1990-12-01), Meyer et al.
patent: 5071646 (1991-12-01), Malkowska et al.

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