Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1992-06-26
1994-09-27
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424 781, 424502, 424 7816, A61K 914, A61K 918
Patent
active
053505840
ABSTRACT:
The invention comprises a novel process for the spheronization of charged resins. Spherical multiparticlates are produced which range in size from 0.3 mm to 3 mm in diameter. The spherical particle product is microcrystalline-free. The process consists of the steps of mixing followed by wet granulation, spheronization and drying.
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patent: 4808413 (1989-02-01), Joshi et al.
patent: 4851421 (1989-07-01), Iwasaki et al.
patent: 4938967 (1990-07-01), Newton et al.
patent: 4976949 (1990-12-01), Meyer et al.
patent: 5071646 (1991-12-01), Malkowska et al.
McClelland Gregory A.
Zentner Gaylen M.
Bigley Francis P.
Daniel Mark R.
DiPrima Joseph F.
Kulkosky Peter F.
Merck & Co. , Inc.
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