Specific salt, anhydrous and crystalline form of a...

Details Specific salt, anhydrous and crystalline form of a... Specific salt, anhydrous and crystalline form of a...

2007-01-30

2008-10-21

Berch, Mark L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S257000, C544S326000, C544S400000, C544S402000, C564S166000

Reexamination Certificate

active

07439358

ABSTRACT:
The present invention relates to a specific salt of a dihydropteridione derivative, namely the trihydrochloride salt of the compound N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to its crystallisation in the form of an hydrate with water, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.

REFERENCES:
patent: 6806272 (2004-10-01), Bauer et al.
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patent: 2006018220 (2006-02-01), None
International Search Report (PCT/ISA/206) for corresponding International Application PCT/EP2007/051139.

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