Specific antibodies against an epitope existing within the A/B r

Details Specific antibodies against an epitope existing within the A/B r Specific antibodies against an epitope existing within the A/B r

1995-07-31

1998-04-28

Feisee, Lila

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

435331, 435332, 53038822, 5303879, C07K 1628, C12N 512

Patent

active

057443564

ABSTRACT:
A unique monoclonal antibody is provided for determining the functional status of human estrogen receptor protein. The monoclonal antibody will specifically bind and react with an epitope present within the transactivation function, A/B domain of the human estrogen receptor protein. The functional status of the A/B domain is determined by identifying and discriminating among the 8S, 4S, 5S isoforms of the A/B region as these exist in the human estrogen receptor protein.

REFERENCES:
patent: 5312752 (1994-05-01), Wotiz

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