Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-04-01
2000-05-16
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546199, A61K 31445, C07D21114, C07D21140
Patent
active
06063796&
ABSTRACT:
This invention relates to somatostatin agonist compounds which are potent with high selectivity toward the receptor subtype 2. Compounds of the formula: ##STR1## including pharmaceutically acceptable salts and hydrates thereof are disclosed. These compounds are useful in the treatment of diabetes, cancer, acromegaly, restenosis, depression, irritable bowel syndrome, pain and diabetic retinopathy. Many of the compounds are also orally active.
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Berk Scott
Chapman Kevin
Chen Meng Hsin
Guo Liangqin
Johnston David
Chang Ceila
McGinnis James L.
Merck & Co. , Inc.
Rose David L.
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