Soluble inhibitors of vascular endothelial growth factor and...

Details Soluble inhibitors of vascular endothelial growth factor and... Soluble inhibitors of vascular endothelial growth factor and...

2007-08-17

2010-06-15

Huynh, Phuong (Department: 1644)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

C424S185100, C530S350000

Reexamination Certificate

active

07736655

ABSTRACT:
The present invention relates to cDNA encoding a soluble neuropilin protein (sNP) which is isolated from neuropilin (NP) producing cells or is recombinantly engineered from NP-encoding DNA. NP-1 and NP-2 are preferred NPs but any neuropilin or VEGF receptor (VEGFR), where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.

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