Soluble compositions of triphenylethylene antiestrogens

Details Soluble compositions of triphenylethylene antiestrogens Soluble compositions of triphenylethylene antiestrogens

2005-05-03

2005-05-03

Henley III, Raymond J. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S422000, C514S428000, C514S648000

Reexamination Certificate

active

06887888

ABSTRACT:
Aqueous compositions of nonsteroidal triphenylethylene antiestrogens for pharmaceutical use comprising as a solubility enhancing agent a pharmaceutically acceptable mono- or dicarboxylic acid having 1-5 carbon atoms, wherein the carbon chain may further contain 1-4 hydroxyl, 1-3 oxo, or one or several halogen substituents, or a corresponding anion thereof, or methanesulfonic acid or its corresponding anion, in molar excess with respect to the triphenylethylene antiestrogen, optionally together with an organic water miscible co-solvent such as polyethylene glycol (PEG), propylene glycol, ethanol or isopropanol.

REFERENCES:
patent: 4919937 (1990-04-01), Mauvais-Jarvis et al.
patent: 5571534 (1996-11-01), Jalonen et al.
patent: 5827892 (1998-10-01), Löser et al.
patent: 5859003 (1999-01-01), Hettche et al.
patent: 5904930 (1999-05-01), Fischer et al.
patent: 6491951 (2002-12-01), Af Ursin et al.
patent: 6632841 (2003-10-01), Af Ursin et al.
patent: 293 263 (1991-08-01), None
patent: 0 240 131 (1987-10-01), None
patent: 0 826 682 (1998-03-01), None
patent: 0 839 533 (1998-05-01), None
patent: 0 842 659 (1998-05-01), None
patent: 0 893 121 (1999-01-01), None
patent: WO 9204310 (1992-03-01), None
patent: WO 9319746 (1993-10-01), None
patent: WO 9416733 (1994-08-01), None
patent: WO 9924032 (1999-05-01), None
Paul Heinz et al., “Ein Lehrbuch for Pharmazeuten”, Wissenschaftliche Verlagsgesellschaft mbH Suttgart, pp. 202-203 (1985) and Eglish translation thereof.
Derwent Abstract of DE 293 263 (Publication date not available).

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