Solid-phase reactions

Details Solid-phase reactions Solid-phase reactions

2002-07-17

2009-02-03

Horlick, Kenneth R. (Department: 1637)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

Reexamination Certificate

active

07485443

ABSTRACT:
The present invention relates to systems, compositions, and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for attaching nucleic acids to solid supports and modifying nucleic acids. For example, in some embodiments, the 5′ nuclease activity of a cleavage agent is used to cleave a cleavage structure formed on the solid support, the occurrence of the cleavage event indicating the presence of specific nucleic acid sequences.

REFERENCES:
patent: 5846717 (1998-12-01), Brow et al.
patent: 5985557 (1999-11-01), Prudent et al.
patent: 5994069 (1999-11-01), Hall et al.
patent: 6001567 (1999-12-01), Brow et al.
patent: 6060288 (2000-05-01), Adams et al.
patent: 6090543 (2000-07-01), Prudent et al.
patent: 6194149 (2001-02-01), Neri et al.
patent: 6348314 (2002-02-01), Prudent et al.
patent: 6372424 (2002-04-01), Brow et al.
patent: 6458535 (2002-10-01), Hall et al.
patent: 6500622 (2002-12-01), Bruchez et al.
patent: 2003/0044796 (2003-03-01), Neri et al.
patent: 2003/0104470 (2003-06-01), Fors et al.
patent: 2004/0018491 (2004-01-01), Gunderson et al.
patent: WO 98/15267 (1998-04-01), None
patent: WO 97/27214 (1998-07-01), None
patent: WO 98/42873 (1998-10-01), None
patent: WO 98/50403 (1998-11-01), None
Sojka et al. Evaluating the quality of oligonucleotides that are immobilized on glass supports for biosensor development. Analytica Chimica Acta vol. 395, 273-284, 1999.
Fors et al. Large-scale SNP scoring from unamplified genomic DNA. Pharmacogenomics, vol. 1, No. 2, pp. 219-229, 2000.
Brookes, A.J., The Essence of SNPs. Gene, vol. 234, pp. 177-186, 1999.
Kremsky et al. Immobilization of DNA via oligonucleotides containint an aldehyde or carboxylic acid group at the 5′ terminus. Nucleic acids Research, vol. 15, No. 7, pp. 2891-2909, 1987.
Lyamichev et al., Nat. Biotech., 17:292 (1999).
Hall et al., PNAS, USA, 97:8272 (2000).
Agarwal et al., Diagn. Mol. Pathol. 9:158 [2000].
Cooksey et al., Antimicrob. Agents Chemother. 44:1296 [2000].
Griffin and Smith, Trends Biotechnol., 18:77 [2000].
Griffin and Smith, Analytical Chemistry 72:3298 [2000].
Hessner et al., Clin. Chem. 46:1051 [2000].
Ledford et al., J. Molec. Diagnostics 2,:97 [2000].
Lyamichev et al., Biochemistry 39:9523 [2000].
Mein et al., Genome Res., 10:330 [2000].
Neri et al., Advances in Nucleic Acid and Protein Analysis 3826:117 [2000].
Fors et al., Pharmacogenomics 1:219 [2000].
Griffin et al., Proc. Nat. Acad. Sci. USA 96:6301 [1999].
U.S. Appl. No. 09/732,622, filed Dec. 8, 2002.
U.S. Appl. No. 09/713,601, filed Nov. 15, 2001.
Kwiatkowski et al., Mol. Diagn. 4:353 [1999].
Ryan et al., Mol. Diagn. 4:135 [1999].
Ma et al., J. Biol. Chem., 275:24693 [2000].
Reynaldo et al., J. Mol. Biol., 297:511 [2000].
Kaiser et al., J. Biol. Chem., 274:21387 [1999].

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