Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1990-05-21
1992-09-22
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 734, 435 792, 435 36, 435970, 435971, 436518, 436527, 436528, 436531, 436535, 436530, 422 56, 422 58, 422 60, 422 61, C12Q 170, C12Q 114, G01N 2100
Patent
active
051496224
ABSTRACT:
A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens or antibodies, is disclosed. The material comprises a porous matrix of fibers and a plurality of substantially spherical, solid particles having an average diameter of from about 0.1 to about 5 microns. The particles are retained and immobilized upon the fibers of the matrix. Preferably, the particles have on their surfaces a substance capable of reaction with the analyte in the sample, and the average diameter of the particles is less than the average pore size of the matrix. The device, in a preferred embodiment, comprises a substantially planar layer of the described material.
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Product Brochure for Abbott Test Pack, Abbott Laboratories, North Chicago, Ill., Aug. 1986.
Brown William E.
Clemens John M.
Devereaux Sharon M.
Hofler John G.
Knigge Kevin M.
Abbott Laboratories
Brainard Thomas D.
Kepplinger Esther L.
Pope Lawrence S.
Spiegel Carol A.
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