Skin cleaning agents, a process for their production and their u

Details Skin cleaning agents, a process for their production and their u Skin cleaning agents, a process for their production and their u

1996-05-31

1999-04-06

Venkat, Jyotsna

Drug, bio-affecting and body treating compositions

Combustible or chemically reactive to produce a smoke, mist...

514844, 514846, A61K 750

Patent

active

058914498

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION



FIELD OF THE INVENTION

The present invention relates to skin cleaning agents having an improved cleaning action and a gentle behavior to the skin. The present invention further relates to a process for their production and to the use of the agents as flowable hand cleaning agents and heavy-duty hand cleaning agents.


DISCUSSION OF THE BACKGROUND

Hand cleaning agents, in particular for the removal of strongly adhering dirt, have already been used in the industrial sector for some time. Patent application No. WO 91/14 420 describes cleaning agents which, in addition to anionic and/or non-ionogenic surfactants, comprise conventional abrasives, organic solvents in the form of carboxylic acid esters, in particular certain acetates, such as preferably n-butoxy-2-ethoxy-ethyl-acetate and fatty alkanolamides, fatty polyalkanolamides, the ethylene oxide and/or propylene oxide addition products thereof, as well as fatty acid monoglycerides as re-greasing agents. Another preferred, additionally used solvent in these hand cleansing agents is limonene, which is known to have a dermal incompatibility involving a sensitization risk. In order to produce the agents according to WO 91/14 420 in an efficient manner, it is necessary to heat the mixture to temperatures above 50.degree. C. after mixing the raw materials, requiring additional heating energy and involving longer production periods.
Furthermore, hand cleaning agents are known which comprise as solvent component natural oils, such as olive oil, jojoba oil, maca-damia-nuts-oil, and grape-seed oil. These cleaning agents have limited detergent properties due to the interaction between the oil portions and the detergent portions and because of the low soil-removing capacity of the natural oil.
In cosmetics the use of special esters of the adipic acid is known. For instance, owing to its slightly greasing character, di-n-butyl adipate is used in day creams and liquid emulsions as well as in hair sprays and setting lotions as softening component or agent to achieve a superfatted state.
Patent No. GB 1,106,945 describes aqueous shampoo preparations for hair cleaning purposes; they comprise as solvents for fats alkyl esters of the dibasic carboxylic acids, phthalic acid or adipic acid. In hair cleaning and hair conditioning, particularly good results are obtained with dimethyl phthalate, however, there is no reference with respect to skin cleaning, in particular to the cleaning of skin heavily soiled by foreign substances.
EP 229 616 A2 describes bath additives comprising diisopropyl adipate as oil component which deposits on the skin.
EP 513 832 A1 describes pharmaceutical products comprising dibutyl adipate or a combination of dibutyl adipate and isopropyl myristate to improve or to control the skin penetration of a therapeutic agent.
Diisopropyl adipate is additionally used as lubricant in alcoholic lotions, as softener in hair aerosols and as fat factor in hair tonics and as solubilizer for perfumes.
PCT-application No. WO 92/09 265 describes a solvent-containing hand cleaning paste containing as solvent DBE 2, dimethyl adipate, dimethyl glutarate and dimethyl succinate, in an amount up to 54 parts per 100 parts of cleaning agent, as well as isooctyl stearate as additionally required re-greasing agent and bleached kernel or shell flour as mild abrasive.
In EP No. 0166522 A2 a cosmetic preparation for the removal of nail varnish is described, which has also skin cleaning properties and comprises as solvent for the nail enamel esters of dicarboxylic acids, preferably diesters or esters of diols, preferably dioldiesters. The diethyl esters of dicarboxylic acids having up to 6 C-atoms are preferred as dicarboxylic acid esters, and the diacetates of diols having 2 to 6-C-atoms are preferred as diol esters. Additionally, the preparations contain lanolin or other re-greasing components and no abradant.
For this reason, the use of the known solvents in skin cleaning agents has made it necessary until today to compensate their intense effect on

REFERENCES:
patent: 3560614 (1971-02-01), Embring
patent: 4707293 (1987-11-01), Ferro
patent: 5476661 (1995-12-01), Pillai et al.

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