Sensor for antigen-antibody reactions

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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356306, 356307, 356318, 356432, 356433, 356229, 422 8205, 422 8208, 422 8209, 435 722, 435808, 436164, 436172, 436518, 436531, 436533, 436534, 436536, 436538, 436539, 436541, 436805, 436807, G01N 33536, G01N 33558, G01N 33574

Patent

active

056630506

ABSTRACT:
A multi-purpose on-line or field-portable system and method for monitoring the presence and concentration of selected antigen-antibody reactions singly or in combination that result from the presence of specific microorganisms or free antigens present or suspended in aqueous solutions, during a given time period. The detection system comprises a detection column and two sensors mounted around the detection column. Each sensor consists of an electromagnetic radiation source and an appropriate detector for the electromagnetic radiation. The reacted analyte tends to accumulate at the sensor located at the bottom detection column. The lower sensor continually nulls against the upper sensor to subtract any optical effects due to non-reactants in the aqueous process or environmental stream. The response from the detector sensors drive an electric circuit, which provides an output signal. In the on-line automatic version, the signal can drive elements of a process system by switching automated valves.

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patent: 4436827 (1984-03-01), Tamagawa
patent: 4652530 (1987-03-01), Rothman et al.
patent: 4908676 (1990-03-01), Bedell et al.

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