Self-assembled, defective, non-self-propagating lentivirus parti

Details Self-assembled, defective, non-self-propagating lentivirus parti Self-assembled, defective, non-self-propagating lentivirus parti

1992-12-21

1998-05-05

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

Inactivation or attenuation; producing viral subunits

435 691, 435 693, 4351723, 4353201, 930221, C12N 1586, C12N 1563, A61K 3921, C07K 14155

Patent

active

057473242

ABSTRACT:
The present invention provides recombinant DNA viral vectors which co-express lentivirus genes encoding structural and enzymatic polypeptides capable of assembling into defective nonself-propagating viral particles. The viral DNA vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and genes.

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