Self assembled defective non-self propagating lentiviral particl

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4242081, 435239, 4352523, 4353201, C12N 1500, C12N 702, C12N 120, A61K 3921

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active

057363684

ABSTRACT:
Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective non-self-propagating lentiviral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.

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