Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1995-06-07
1998-04-07
Achutamurthy, Ponnathapura
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4242081, 435239, 4352523, 4353201, C12N 1500, C12N 702, C12N 120, A61K 3921
Patent
active
057363684
ABSTRACT:
Recombinant viral vectors which coexpress heterologous polypeptides capable of assembling into defective non-self-propagating lentiviral particles are disclosed. The viral vectors as well as the viral particles can be used as immunogens and for targeted delivery of heterologous gene products and drugs.
REFERENCES:
patent: 4603112 (1986-07-01), Paoletti et al.
S. Hu, et al., Nature, 302:537-540 (1986).
S. Chakrabarti, et al., Nature 320: 535-537 (1986).
M.P. Kieny, et al., Biotechnology, 4:790-795 (1986).
J.M. Zarling, et al., Nature, 323:344-346 (1986).
S. Hu, et al., Nature, 328:721-723 (1987).
D. Zagury, et al., Nature, 326:249-250 (1987).
D. Zagury, et al., Nature, 332:728-731 (1988).
G.L. Smith, et al., Gene, 25:21-28 (1983).
T. Shioda, et al., Virology, 175:139-148 (1990).
D. Panicali, et al., Proc. Natl. Acad. Sci. USA, 79:4927-4931 (1982).
D. Panicali, et al., Proc. Natl. Acad. Sci. USA 80:5364-5368 (1983).
O. Haffar, et al., J. Virol. 64:2653-2659 (1990).
V. Karacostas, et al., Natl. Proc. Acad. Sci. USA, 86:8964-8967 (Nov. 1989).
M. E. Perkus, et al., Science, 229:981-984 (1985).
M. Delchambre, et al., The EMBO J. 8:2653-2660 (1989).
M.L. Bosch et al., Science 244:694-697 (1989).
S.D. Gowda et al., J. Biol. Chem., 264:8459-8460 (May 1989).
G. Rautmann, et al., AIDS Res. Hum. Retroviruses 5:147-157 (Apr. 1989).
S.D. Gowda, et al., J. Virol, 63:1451-1454 (1989).
S.A. Popov, et al., Mol. Gen. Mikrobiol. Virusol. 9:36-39 (Sep. 1988).
C. Flexner, et al., Virology, 166:339-349 (Oct. 1988).
G. Mazzara, et la., Modern Approaches to Vaccines, Cold Spring Harbor Laboratory, New York (1987).
D. Gheysen, et al., Modern Approaches to New Vaccines, Cold Spring Harbor Laboratory, New York, Sep. 14-18, 1988, Abstract No. 72.
International Search Report.
D. Gheysen, et al., Cell 59:103 (1989).
International Preliminary Examination Report.
B.N. Fields, et al., Eds Fundamental Virology, 2nd Ed. New York: Raven Press, 1991, p. 16,92-93.
R. Mann, et al., (1983) Cell 33:153-159.
A. Lever, et al., (1989) J. Virology 63(9):4085-4087.
International Search Report for the corresponding Patent Cooperation Treaty application.
Gritz Linda R.
Mazzara Gail P.
Panicali Dennis L.
Roberts Bryan
Stallard Virginia
Achutamurthy Ponnathapura
Bronstein Sewall P.
Eisenstein Ronald I.
Park Hankyel T.
Resnick David S.
LandOfFree
Self assembled defective non-self propagating lentiviral particl does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Self assembled defective non-self propagating lentiviral particl, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self assembled defective non-self propagating lentiviral particl will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-11834