Selective inhibitors of cyclooxygenase-2

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S235200, C514S241000, C514S252060, C514S254090, C514S256000, C514S255050, C514S323000, C514S339000, C514S414000, C544S062000, C544S144000, C544S238000, C544S333000, C544S373000, C544S405000, C544S215000, C546S208000, C546S277100, C548S468000

Reexamination Certificate

active

06846818

ABSTRACT:
The present invention relates to cyclooxygenase-2 (COX-2) selective inhibitors of formula I:pharmaceutical compositions containing them, to their medicinal use, and to their preparations. The compounds of the invention are particularly useful in the treatment or alleviation of inflammation and inflammation associated disorders, such as, for example, rheumatoid arthritis and osteoarthritis, and in the relief of pain, such as, for example, pain associated with surgery or trauma, in mammals, preferably felines and canines.

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