Organic compounds -- part of the class 532-570 series – Organic compounds – Carbonate esters
Patent
1986-06-10
1992-01-21
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbonate esters
558273, C07C 6996
Patent
active
050829645
ABSTRACT:
A new group of alpha substituted cresol choline carbonate salts, that act as site-specific, irreversible inhibitors of acetylcholinesterase. A halomethylation method and a halogenation method for producing said alpha substituted cresol choline carbonate salts and analogs thereof. Methods of using the inhibitors as anticholinergic insecticides and to reduce acetylcholinesterase activity levels in organisms with excessive levels of acetylcholinesterase.
REFERENCES:
patent: 3134802 (1964-05-01), Gaertner et al.
patent: 3420868 (1969-01-01), Weil
patent: 3598856 (1971-08-01), Fujino et al.
patent: 4260529 (1981-04-01), Letton
Balasubramanian Venkataraman
Burns Hugh D.
Heindel Ned D.
Turizo Miguel
Dees Jos,e G.
Lehigh University
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