Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2007-12-11
2007-12-11
Romeo, David (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S387300, C530S388100, C530S388230, C530S389100, C530S389200, C530S391300
Reexamination Certificate
active
10970823
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
Hudson, T., Human STS WI-8719, Sequence Tagged Site, GenBank Database Accession No. G06979, National Center for Biotechnology, Bethesda, MD. Oct. 19, 1995.
Koehrer, et al., Direct Submission, GenBank Database Accession No. AL050275, National Center for Biotechnology Information, Bethesda, MD. Mar. 10, 2001.
Koehrer, et al., Direct Submission, GenBank Database Accession No. T08724, National Center for Biotechnology Information, Bethesda, MD. Jun. 11, 1999.
Chen, et al., Direct Submission, GenBank Accession No. U48852, National Center for Biotechnology Information Bethesda, MD, Mar. 7, 1996.
Pennica, et al., “WISP Genes are Members of the Connective Tissue Growth Factor Family that are Up-Regualted in WNT-1, Transformed Cells and Aberrantly Expressed in Human Colon Tumors”, Proceedings of the National Academy of Science, USA, 95(25):14717-14722, Dec. 8, 1998.
Campbell, et al., “Epidermal Growth Factor-Like Modules”, Curr. Opin. Struct. Bio., 3:385-392, 1993.
Appella, et al., “Structure and Function of Epidermal Growth Factor-Like Regions in Proteins” FEBS Lett., 231(1):1-4, Apr. 11, 1988.
Bender, W., “Homeotic Gen Products as Growth Factors”, Cell. 43 (3 Pt. 2):559-560, Dec. 1985.
Lecka-Czernik, et al., “An Overexpressed Gene Trasncript in Senescent and Quiescent Human Fibroblasts Encoding a Novel Protein in the Epidermal Growth Factor-Like Reapet Family Stimulates DNA Synthesis”, Mol. Cell. Biol. 15(1):120-128, Jan. 1995.
Engel, “EGF-Like Domains in Extracellular Matrix Proteins: Localized Signals for Growth and Differentiation?” FEBS Lett., 251(1-2): Jul. 17, 1989.
Ashkenazi et al; “Sixty one nuleic acids encoding PRO polypeptides which are useful in the treatment of skin diseases, cancers and neurodegenerative diseases”, P—AAF72391; WO200104311-A1, Feb. 22, 2000; Pub Date Jan. 18, 2001.
Botstein et al; “New antibody that binds to a PRO polypeptide, useful for diagnosing and treating cancers”, P—AAF60352; WO200105836-A1, Dec. 20, 1999; Pub Date Jan. 25, 2001.
Goddard et al; “New isolated antibodies which bind to specific polypeptides used for diagnosis and treatment of neoplastic cell growth and proliferation”; P—AAA30032; WO200015666-A2, Sep. 8, 1999; Pub Date Mar. 23, 2000.
Ashkenazi et al; “Nucleic acids encoding PRO polypeptides useful for preventing, diagnosing and treating diagnosing a cardiovascular, endothelial or angiogenic disorders in mammals”, P—AAA77541; WO200032221-A2, Nov. 30, 1999; Pub Date Jun. 8, 2000.
Botstein et al; “Antibodies against specific proteins overexpressed in tumours”, P—AAX28431; WO9914327-A2, Sep. 10, 1998; Pub Date Mar. 25, 1999.
Chen, et al; “New isolated human genes and polypeptides used in, e.g. treatment of gastrointestinal ulceration”, P—AAX52233; WO9914328-A2, Sep. 16, 1998; Pub Date Mar. 25, 1999.
Botstein et al; “Polypeptidic ccompositions and methods for the treatment of tumors”, AX076899; WO 0105836-A 11, Jan. 25, 2001.
Pan, Y and Leiby, K.R.; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAC84379; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Bandman et al; “Isolated polynucleotide encoding extracellular matrix or adhesion-associated protein (EXMAD) useful for diagnosing, treating, or preventing disorders associated with expression of EXMAD such as proliferative, immune and genetic disorders”, P—AAC66895; WO200068380-A2, May 10, 2000; Pub Date Nov. 16, 2000.
Pan, Y and Leiby, K.R.; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAC84403; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Pan, Y and Leiby, K.R.; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAC84401; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Bandman et al; “Extracellular matrix and adhesion-associated proteins”, AX047345; WO 0068380-A 31, Nov. 16, 2000.
Rupp et al; “Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins”, NM—015513; Gene 293 (1-2), 47-57 (2002).
Wiemann et al; “Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs”, HSM800381; Genome Res.11(3), 422-435 (2001).
Bandman et al; “Isolated polynucleotide encoding extracellular matris or adhesion-associated protein (EXMAD) useful for diagnosing, treating, or preventing disorders associated with expression of EXMAD such as proliferative, immune and genetic disorders”, P—AAB27228; WO200068380-A2, May 10, 2000; Pub Date Nov. 16, 2000.
Ashkenzai et al; Sixty one nucleic acids encoding PRO polypeptides which are useful in the treatment of skin diseases, cancers and neurodegenerative diseases, P—AAB80230; WO200104311-A1, Feb. 22, 2000; Pub Date Jan. 18, 2001.
Botstein, et al; “New antibody that binds to a PRO polypeptide, useful for diagnosing and treating cancers”, P—AAB68594; WO200105836-A1, Dec. 20, 1999; Pub Date Jan. 25, 2001.
Goddard et al; “New isolated antibodies which bind to specific polypeptides used for diagnosis and treatment of neoplastic cell growth and proliferation”, P—AAY88569; WO200015666-A2, Sep. 8, 1999; Pub Date Mar. 23, 2000.
Ashkenzai et al; “Nucleic acids encoding PRO polypeptides useful for preventing, diagnosing and treating diagnosing a cardiovascular, endothelial or angiogenic disorders in mammals”, P—AAB24396; WO200032221-A2, Nov. 30, 1999; Pub Date Jun. 8, 2000.
Botstein et al; “Antibodies against specific proteins overexpressed in tumours”, P—AAY05281; WO9914327-A2, Sep. 10, 1998; Pub Date Mar. 25, 1999.
Chen et al; “New isolated human genes and polypeptides used in, e.g. treatment of gastrointestinal ulceration”, P—AAY13362; WO9914328-A2, Sep. 16, 1998; Pub Date Mar. 25, 1999.
Pan and Leiby; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAB48106; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Pan and Leiby; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAB48135; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Pan and Leiby; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAB48134; WO200069885-A2, May 15, 2000; Pub Date Nov. 23, 2000.
Pan and Leiby; “Novel nucleic acids encoding secreted or transmembrane proteins, useful for treating, e.g. cancer, hemophilia, anemia, ischemia or diseases of the lung, liver, kidney or pancreas”, P—AAB48133; WO200069885-A2, Ma
Desnoyers Luc
Ferrara Napoleone
Filvaroff Ellen
Goddard Audrey
Godowski Paul J.
Barnes Elizabeth M.
Dreger Ginger R.
Genentech Inc.
Kresnak Mark T.
Romeo David
LandOfFree
Secreted and transmembrane polypeptides and nucleic acids... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Secreted and transmembrane polypeptides and nucleic acids..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Secreted and transmembrane polypeptides and nucleic acids... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3887545