Scaled-up production of liposome-encapsulated hemoglobin

Details Scaled-up production of liposome-encapsulated hemoglobin Scaled-up production of liposome-encapsulated hemoglobin

1986-08-29

1988-10-11

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 41, 264 46, 424450, 4284022, 436829, 514 6, 514832, 514833, A61K 942, A61K 3722, B01J 1302

Patent

active

047769912

ABSTRACT:
A method for making sterile liposome-encapsulated hemoglobin having an oxn carrying capacity of 20 vol/%, a half life of 15-20 hours as measured in mice, with the liposome made from chloroform, HSPC, cholesterol, negatively charged DMPG and alpha-tocopherol.

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patent: 4448765 (1984-05-01), Ash et al.
patent: 4515736 (1985-05-01), Deamer
patent: 4529561 (1985-07-01), Hunt et al.
patent: 4532130 (1985-07-01), Djordjevich et al.
patent: 4649151 (1987-03-01), Dougherty et al.

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