Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-06-22
1995-11-14
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514312, 548210, 546155, 546156, 546157, 546280, 546283, 546198, 544282, 544116, 544362, A61K 31425, C07D27506, C07D21316, C07D23970
Patent
active
054667011
ABSTRACT:
Compounds having the structural formula ##STR1## which inhibit the enzymatic activity of proteolytic enzymes, and processes for preparation thereof, method of use thereof in treatment of degenerative diseases and pharmaceutical compositions thereof are disclosed.
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Merck Index, 10th ed. 1983, Pub. Merck and Co., Inc. Rahway, N.J.; p. ONR96.
Sunkel et al., J. Med. Chem. 31 1886-1890 (1988).
Ackerman James H.
Desai Ranjit C.
Hlasta Dennis J.
Mura Albert J.
Alexander Michael D.
Brust Joseph Paul
Cross Laura
DuPont Paul E.
Sterling Winthrop Inc.
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