Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Patent
1996-10-28
1999-07-20
Minnifield, Nita
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
4242351, 4242341, 424 931, 424 932, 424 934, A61K 3900, A61K 3938, A61K 4800, A61K 3902
Patent
active
059253541
ABSTRACT:
Described is a vaccine against Actinobacillus pleuropneumoniae (APP) comprising genetically defined biochemically attenuated mutant of APP that requires riboflavin and is attenuated in vivo.
REFERENCES:
patent: 4888170 (1989-12-01), Curtiss, III
patent: 5120655 (1992-06-01), Foster et al.
patent: 5332572 (1994-07-01), Ross et al.
patent: 5387744 (1995-02-01), Curtiss, III et al.
patent: 5389368 (1995-02-01), Gurtiss, III
patent: 5424065 (1995-06-01), Curtiss, III
patent: 5429818 (1995-07-01), Inzana
patent: 5456914 (1995-10-01), Stine et al.
patent: 5468485 (1995-11-01), Curtiss, III
patent: 5543304 (1996-08-01), Mulks et al.
Inzana et al, Infect + Immunity. 61/5:1682-1686, May 1993.
"Characterization of Actinobacillus pleuropneumoniae Riboflavin Biosyntesis Genes", Troy E. Fuller et al., J. Bacteriology, Dec. 1995, pp. 7265-7270.
"A Targeted Mutagenesis System For Actinobacillus pleuropneumoniae", Martha H. Mulks et al., Gene, 165 (1995) 61-66.
"Biosynthesis of Riboflavin, Biotin, Folic Acid, and Cobalamin", John B. Perkins et al., Bacillus subtilis, 23 (1993), 319-335.
"Sequencing of the Riboflavin Operon Genes From Actinobacillus.", R.E. Fuller et al., General Meeting Abstracts, 95.sup.th.
Fuller et al. Inf +Imm. 64/11:4659-4664, 1996.
Lee et al. BBRC 186/2:690-697, 1992.
Inzana, Microbial Pathogenesis 11:305-316, 1991.
Bresler et al, Genetika 5:133-138, 1969.
Fuller et al. IN: Haemophilus, Actinobacillus, and Pasteurella ed. Domachie et al pp. 229-230, 1994.
Fuller et al ASM Mtg 1995. Abstract. B-344 p. 183 1995.
Lee et al. J. Bacterial, 176/7:2100-2104, 1994.
Fuller Troy E.
Mulks Martha H.
Thacker Bradley
Michigan State University
Minnifield Nita
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