Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1988-08-17
1991-06-18
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 530330, 530331, 544 86, 544162, 548561, 558 5, 560 28, 560 39, 564 28, 564104, 564108, 564153, A61K 3702, C07K 500
Patent
active
050249940
ABSTRACT:
The invention concerns novel renin-inhibitory peptides which are useful for treating renin-assocated hypertension, hyperaldosteronism, and congestive heart failure. Processes for preparing the peptides, compositions containing them and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension or hyperaldosteronism.
REFERENCES:
patent: 4609641 (1986-09-01), Evans et al.
Haber et al., J. Cardiovasc. Pharmacol., 1987, 10(Suppl. 7):554-558.
Burger, Medicinal Chemistry, 1960, pp. 565-571, 578-581, 600-601.
Denkewalter et al., Progress in Drug Research, vol. 10, 1966, pp. 510-512.
Plattner et al., J. Med. Chem., 31(12), 1988, pp. 2277-2288.
Doherty Annette M.
Hudspeth James P.
Kaltenbronn James S.
Repine Joseph T.
Roark William H.
Anderson Elizabeth M.
Lee Lester L.
Maebius Stephen B.
Warner-Lambert & Company
LandOfFree
Renin inhibitors IV does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Renin inhibitors IV, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Renin inhibitors IV will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-145828