Renin inhibiting N-(2-amino-2-oxoethyl)butanediamide derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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5142312, 5142315, 5142318, 514315, 514336, 514342, 514381, 514382, 514396, 514408, 514439, 514461, 544106, 544124, 544133, 544159, 546184, 548146, 548250, 5483001, 548400, A61K 3800

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055411630

ABSTRACT:
Disclosed herein are compounds of the formula:

REFERENCES:
patent: 5006511 (1991-04-01), Greenlee
patent: 5055466 (1991-10-01), Weller
patent: 5063208 (1991-11-01), Rosenberg
Chemical Abstracts, vol. 119, No. 5, (Aug. 1993) p. 910, Abstract No. 49082t; "Preparations of (Naphthlymethyl)Amine Derivatives as Renin Inhibitors", N. Nakada et al.
Medicinal Research Reviews, Col. 10, No. 2, 173-236 (1990); "Renin Inhibitors", William J. Greenlee.

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