Fluid sprinkling – spraying – and diffusing – Processes – Involving slow diffusion
Patent
1999-02-18
2000-08-29
Morris, Lesley D.
Fluid sprinkling, spraying, and diffusing
Processes
Involving slow diffusion
239 515, 239 55, 239 57, 239 58, A61L 904
Patent
active
061095370
ABSTRACT:
A release rate modulator for use with membrane-based formulations systems to control the release of a substance. The release rate modulator is formed from perforated polypropylene containing approximately 36 holes/cm.sup.2. Each hole is approximately 1 mm.sup.2 in size. The flow of substance passes through the holes and the membrane before reaching the surrounding environment. The use of the modulator improves the duration of substance release and provides a more constant release of the substance compared to unpredictable release rates obtained when the formulations systems did not contain the modulator.
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Fado John D.
Morris Lesley D.
Silverstein M. Howard
Stover G. Byron
The United States of America as represented by the Secretary of
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